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Ethionamide may be bacteriostatic or bactericidal in actiondepending on the concentration of the drug attained at the site of infection and the susceptibility of the infecting organismEthionamidelike prothionamide and pyrazinamideis a nicotinic acid derivative related to isoniazidIt is thought that ethionamide undergoes intracellular modification and acts in a similar fashion to isoniazidIsoniazid inhibits the synthesis of mycoloic acidsan essential component of the olanzapine no prescription. bacterial cell wallSpecifically isoniazid inhibits InhAthe enoyl reductase from Mycobacterium tuberculosisby forming a covalent adduct with the NAD cofactorIt is the INH-NAD adduct that acts as a slowtight-binding competitive inhibitor of InhA.

FDA pregnancy category CIt is not known whether ethionamide will harm an unborn babyTell your doctor if you are pregnant or plan to become pregnant while using ethionamide.

Take this medication by mouth with or without foodusually once daily or as directed by your doctorIf this medication causes stomach upset or nausea/vomitingtake this medication with mealsAlsodiscuss with your doctor if it may be helpful to divide your daily dose into smaller doses to be taken several times a dayFollow your doctor’s instructions carefully.

FDA pregnancy category CIt is not known whether ethionamide will harm an unborn babyTell your doctor if you are pregnant or plan to become pregnant while using ethionamide.

Take a missed dose as soon as you think about itIf it is close to the time for your next doseskip the missed dose and go back to your normal timeDo not take 2 doses at the same time or extra doses.

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