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Take after meals. To gain the most benefit.do not miss doses. Keep taking Zyloprim (allopurinol tablets) as you have been told by your doctor or other health care provider.even if you feel well. Keep taking Zyloprim (allopurinol tablets) even if you are having a gout attack. Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.

The reports that the concomitant use of ZYLOPRIM and thiazide diuretics may contribute to the enhancement of allopurinol toxicity in some patients over the counter zyloprim been reviewed in an attempt to establish a cause-and-effect relationship and a mechanism of causation. Review of these case reports indicates that the patients were mainly receiving thiazide diuretics for hypertension and that tests to rule out decreased renal function secondary to hypertensive nephropathy were not often performed. In those patients in whom renal insufficiency was documented.however.the recommendation to lower the dose of ZYLOPRIM was not followed. Although a causal mechanism and a cause-and-effect relationship have not been established.current evidence suggests that renal function should be monitored in patients on thiazide diuretics and ZYLOPRIM even in the absence of renal failure.and dosage levels should be even more conservatively adjusted in those patients over the counter zyloprim such combined therapy if diminished renal function is detected.


During concomitant treatment.reduce dosages of azathioprine and mercaptopurine to 25-33% of usual.

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